Human Dosimetry of the N-Methyl-d-Aspartate Receptor Ligand 11C-GMOM
نویسندگان
چکیده
منابع مشابه
Quantification of the novel N-methyl-d-aspartate receptor ligand [11C]GMOM in man
[(11)C]GMOM (carbon-11 labeled N-(2-chloro-5-thiomethylphenyl)-N'-(3-[(11)C]methoxy-phenyl)-N'-methylguanidine) is a PET ligand that binds to the N-methyl-d-aspartate receptor with high specificity and affinity. The purpose of this first in human study was to evaluate kinetics of [(11)C]GMOM in the healthy human brain and to identify the optimal pharmacokinetic model for quantifying these kinet...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2017
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.116.188250